Infected Joint Replacement: What an Antibiotic Spacer Does

/Revision Joint Replacement

Illustration of a knee joint with a temporary antibiotic spacer in place
Illustration of a knee joint with a temporary antibiotic spacer in place

Hearing that your joint replacement is infected is frightening. You went through surgery, rehab and months of effort, and now the doctor is talking about taking the implant out and putting in something called a spacer.

It helps to know that this is a recognised, well-planned treatment, and that most infections can be cleared. Understanding each step makes the process much less scary.

This article explains how an infected joint replacement is treated, what an antibiotic spacer actually does, and what you can expect along the way.

What Is an Infected Joint Replacement?

An infection happens when bacteria settle on the artificial joint. It can appear within a few weeks of surgery, or months or even years later. Because the implant has no blood supply of its own, the body's defences and ordinary antibiotics struggle to reach bacteria that stick to it.

Treatment usually means revision surgery, which is a further operation to wash out the joint or to replace the implant. You can read about this on our page for revisional joint replacement in Ahmedabad.

Depending on the joint involved, you can also read about revision knee replacement, revision hip replacement in Ahmedabad or revision shoulder replacement. Infection is only one reason for a second operation, and our blog on why joint replacements need revision surgery explains the others.

Signs of an Infected Joint Replacement

Some infections are obvious, but others are quiet. Look out for:

  • Warmth, redness or swelling around the joint
  • Fluid or discharge from the wound
  • Fever or chills
  • Pain or stiffness that keeps increasing, even without a fever

Warmth, redness, discharge or fever need urgent assessment. A low-grade infection may cause only pain and stiffness, which is why persistent pain after replacement should never be ignored. Our articles on early signs of a failing knee replacement and early signs of revision hip replacement explain more.

How Do Doctors Confirm an Infection?

No single test is perfect, so doctors combine several.

TestWhat it showsGood to know
Blood tests (ESR and CRP)Signs of inflammation in the bodyCan be normal in a low-grade infection, especially in the shoulder
X-ray or other scansLoosening, bone changes or fluid around the implantCan't prove infection on their own
Joint fluid or tissue sampleWhether bacteria are present, and which typeCultures may be kept longer because some bacteria grow slowly

Antibiotics should generally wait until samples are taken, unless your doctor advises otherwise, because starting early can hide the bacteria and make the diagnosis harder.

How Is an Infected Joint Replacement Treated?

The treatment depends on how long the infection has been there, which bacteria are involved, the condition of the soft tissues and your general health.

SituationTreatmentWhat happens
Early infection, within a few weeks of surgeryWash-out and implant keptThe joint is washed out, removable parts are changed, and antibiotics are given
Long-standing infection, one-stage approachSingle-stage revisionThe infected implant is removed and a new one is fitted in the same operation
Long-standing infection, two-stage approachTwo-stage revisionThe implant is removed, a temporary spacer is placed, and a new implant follows later

Antibiotics are usually given for several weeks in each case. A team approach also helps, and may include an orthopaedic surgeon, a microbiologist and an infectious diseases physician.

Each member has a clear role. The microbiologist identifies the germ and checks which antibiotics work against it, while the infectious diseases physician helps choose the medicine, the dose and how long to continue. Your surgeon then plans each operation around those results, so decisions are shared and never rushed.

What Does an Antibiotic Spacer Do?

This is the part that confuses most patients. An antibiotic spacer is a temporary block made from bone cement mixed with a high dose of antibiotics. The surgeon places it in the joint after removing the infected implant.

It does two jobs:

  • It releases antibiotics slowly, over about six weeks, straight into the infected area
  • It keeps the joint space open, so the tissues don't shrink and the later reconstruction is easier

Keeping the space open also lets many patients move about with a walker rather than staying in bed. Spacers are made in different forms, such as hand-moulded, ready-made or custom-shaped in the operating theatre, and some knee spacers allow a little bending.

Illustration of an antibiotic cement spacer placed in a knee after infected implant removal
Illustration of an antibiotic cement spacer placed in a knee after infected implant removal

The Two-Stage Journey, Step by Step

For a long-standing infection, many surgeons prefer two stages. Here's how it usually unfolds.

StageWhat happensRoughly how long
Stage 1The infected implant is removed, the joint is cleaned and the spacer is placed, with antibiotics through a dripOne operation
Waiting periodAntibiotics continue while the infection clears and the spacer worksAbout six weeks in one study
Stage 2Once the infection is gone, the spacer is removed and a new implant is fittedOne operation

In one well-known study, the whole process took about a year from start to finish. Your own timeline depends on your joint, your bacteria and how well your body responds.

Living With a Spacer

Between the two operations, the joint has limited use, and this period needs patience. After a knee or hip revision, you may walk with support and sometimes with limited weight on the leg. After a shoulder revision, a sling is often needed for longer than after a first replacement.

To get through it safely:

  • Follow your weight-bearing instructions exactly
  • Take every antibiotic dose as prescribed
  • Report fever, new redness or wound discharge straight away
  • Keep all your follow-up and blood test appointments
  • Do the exercises your physiotherapist gives you

Blood clots in the leg or arm veins and lungs are possible, so keep moving as advised. PMG Hospital has an orthopaedic physiotherapy centre in Gota for rehabilitation after revision surgery.

How Well Does Treatment Work?

Reported success is encouraging. In the study mentioned above, antibiotic spacers cleared the infection in more than 90% of patients with knee and hip replacements, and a review of spacer use in hip and knee infections also reports control rates above 90% with two-stage exchange. The review adds that results differ between studies, so exact figures are hard to pin down.

It isn't risk-free. Sometimes infection returns or can't be cleared, which may mean further surgery, a permanent spacer or removal of the implant. Spacers can also dislocate or fracture, and the antibiotics in the cement can rarely cause problems for the kidneys, liver or blood. These are reasons to be treated by an experienced team.

Your own health also matters. If you have diabetes, smoke or live with other medical problems, tell the team early, because these can affect healing and the chance of clearing the infection. Steady blood sugar, good nutrition and staying active within your limits give the new implant a better start.

If you have a joint replacement and notice warmth, redness, discharge or fever, don't wait. Emergency care is available 24×7 at PMG Hospital, and for any other worry about your joint you can book a consultation. If you've been advised revision and want another view, a second opinion is a sensible step.

Frequently Asked Questions

What is an antibiotic spacer?

An antibiotic spacer is a temporary block of bone cement mixed with antibiotics. It's placed in the joint after an infected implant is removed, to release medicine slowly and keep the joint space open.

How long does an antibiotic spacer stay in?

Usually about six weeks, though your surgeon decides based on how the infection responds. A new implant is fitted in the second operation once the infection has cleared.

Can an infected joint replacement be saved without removing it?

Sometimes. An early infection, within a few weeks of surgery, may be treated by washing out the joint, changing removable parts and giving antibiotics while keeping the implant.

Can I walk with an antibiotic spacer?

Many people can, using a walker or other support, and sometimes with limited weight on the leg. Follow your surgeon's exact instructions.

Does an infected joint replacement always cause fever?

No. A low-grade infection may cause only increasing pain and stiffness, and blood tests can still look normal, so persistent pain should always be checked.

Conclusion

An infected joint replacement is serious, but it's treatable. Early infections can sometimes be cleared with a wash-out while the implant stays. Long-standing ones often need the implant removed, with an antibiotic spacer holding the space and delivering medicine while the infection clears, before a new implant is fitted.

The process takes time and patience, but most patients get through it with the right team. If you're worried about your joint replacement or have been told you may need revision, the team at PMG Hospital can examine you, explain each step in plain words and plan your treatment with you.

Appointments

Book a Consultation at PMG Hospital

Share your details and our patient care team will call you back to schedule an assessment, review your reports or arrange a second opinion.

What happens next

  1. 1We call you back the same working day to fix a time.
  2. 2Bring your X-rays, MRI and previous prescriptions to the visit.
  3. 3You leave with a clear plan - and an honest answer on whether surgery is needed.

Request a call back

Our patient care team responds the same working day.

Your details are used only to arrange this consultation.

Medically reviewed by Dr. Hiren Patel, MS (Ortho.), Joint Replacement Surgeon, PMG Hospital, Ahmedabad.

Call WhatsAppBook